本剧改编自同名漫画，讲述专门解决办公室不伦问题的“职场空气净化师”三枝玲（山崎纮菜 饰），以干净利落的手段拆散扰乱公司秩序的出轨男女，守护职场清朗风气。她的搭档鹿妻新（饭岛宽骑 饰）擅长伪装接近目标，与玲一同展开击退行动。某日，作为不伦解决委托窗口的“枪酱”的师傅——酒吧“PURPLE ROSE”的老板（马克·朋沙 饰）现身，宣布枪酱外出修行，并主动接手窗口工作。
SHAMELESS tells the story of a young group of siblings pretty much abandoned by their parents, surviving by their wits - and humour - on a rough Manchester council estate. Whilst they won't admit it, they need help and find it in Steve, a young middle class lad who falls for Fiona (Anne-Marie Duff'), the oldest sibling, and increasingly finds himself drawn to this unconventional and unique family. Anarchic family life seen through the eyes of an exceptionally bright fifteen year old, who struggles to come of age in the context of his belligerent father, closeted brother, psychotic sister and internet porn star neighbours.
北漂青年祖波是一名程序员，他热爱自己的工作，平时的生活异常简单，除了工作就是呆在“包租婆”波妈慧芳在北京早年购置的房子里钻研写代码。祖波平静的生活，却被波妈的一通电话打破，他被告知广东老家的三叔公要来北京暂住他家，波妈还再三强调，要好好接待三叔公。虽然祖波早已对这位远方亲戚没了印象，但还是做好了准备，推着轮椅去车站接“老人家“。没想到波妈口中的三叔公，其实是一位和祖波同龄的年轻人，只是因为辈分高，成了“叔公”。祖波开始还有些抗拒，在听到叔公也是“程序员”的时候，他放下戒备，带着叔公回了家。
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